We've got CRAPWARE, Spyware, AdWare, Trojans, Worms, Viri, Rookits and all sorts of other bad stuff out there. Now add to it Ransom-Ware. Apparently this beast encrypts all your data and demands a ransom. It appears to be targeted and specific. The US Department of Transportation was caught up, along with a list of corporations that you can find here.
Yikes.